molecular devices spectramax m5e

Single nucleotide polymorphisms (SNPs) are one of the most common types of genetic variation, consisting of a single nucleotide mutation at a specific locus. The Analyst®, FlexStation® and SpectraMax® M5/M5e from Molecular Devices have received the LanthaScreen® Certified designation from Invitrogen™ which ensures that these readers are validated to strict standards in instrument se O…. Green fluorescent protein (GFP) from the jellyfish Aequorea victoria was the…, Cyclic nucleotide phosphodiesterases (PDEs) are a group of enzymes that degrade the phosphodiester bond of cAMP and cGMP, second messengers that are involved in a variety of biological…, HTRF is a versatile technology developed by Cisbio Bioassays for detecting biomolecular interactions1. The Molecular Devices SpectraMAX absorbance microplate readers mimic a dual beam spectrophotometer with a patented multichannel optical design. No. Our comprehensive suite of proven compliance solutions for GMP/GLP labs can advance your efforts to quickly and confidently establish a compliant laboratory. Symptoms of mycoplasma contamination include a reduction in the rate of…, Protein kinases are central to the regulation of many cellular processes. All stand-alone instrument functions can be controlled using the software. We’ll provide applications resources to aid in your research, including kinase assays, cellular signaling pathways, protein-protein interactions, cell cytotoxicity, and more. 美谷分子仪器（上海）有限公司保留所有权利。 All Rights Reserved 沪ICP备05056171号-1, Baicalein is one of the major flavonoids obtained from the Scutellaria root. CRL-1658) Minimum Essential Medium (MEM, Corning Cat. Instrument settings can be saved as a protocol file and used repeatedly for reading different microplates or cuvettes. Chronic kidney disease (CKD) is associated with accelerated atherosclerosis and increased mortality from cardiovascular disease. SpectraMax L* SpectraMax Plus line. Cell viability can be assessed by examining parameters such as cell membrane integrity or the activity of cellular enzymes. Make an Inquiry Add To Watch List. MicroplateReader,SpectraMax®M5Multi-ModeMicroplateReader,andSpectraMax®M5e Multi-ModeMicroplateReaderaredualmonochromator,multi-detectioninstrumentswith atriple-modecuvetteportanda6-wellto384-wellplatereadcapability. Microplate Readers, for their consistent performance, reliability and du…, Mycoplasma, the smallest and simplest of the prokaryotes, are common contaminants of cell cultures. This microplate reader features two monochromators allowing users to define their optimal excitation and emissions without the need to change filters. *Using lowest settings and speed read when available. Baicalein is one of the major flavonoids obtained from the Scutellaria root. 3860 N First Street San Jose, CA 95134. 美谷分子仪器（上海）有限公司保留所有权利。 All Rights Reserved 沪ICP备05056171号-1. Our highly-qualified teams are on the frontlines with our customers, conducting remote or on-site product demonstrations, webinars, and more to help you solve your tough research challenges. CKD results in oxidative stress, inflammation, and high-density lipoprotein (HDL) deficiency, which work in concert to promote atherosclerosis. The purpose of this paper was to explore the molecular mechanism of the action of baicalein on PC12 cells and isolated rat brain mitochondria.…, Tissue accumulation of homocysteine occurs in classical homocystinuria, a metabolic disease characterized biochemically by cystathionine β-synthase deficiency. We’ll cover key luminescence-based assays including dual-luciferase reporter gene, chemiluminescent ELISA, cytotoxicity, and BRET. Biology research has been greatly simplified by the availability of standardized assay kits, instruments, and assay protocols from commercial manufacturers. ©2021 Molecular Devices, LLC. Standard features include a cuvette port, spectral scanning in 1 nm increments, and up to six wavelengths per read. We also provide information on common absorbance applications and assays including ELISAs, nucleic acid and protein quantitation, and microbial growth. The SpectraMax® M5e Multi-Mode Microplate Reader from Molecular Devices delivers single-mode reader performance in one multi-mode reader package. The Molecular Devices Spectramax M5 is a multi-mode plate reader with a dual monochromator. The Molecular Devices SpectraMax M5E is a multi-mode plate reader that delivers single mode reader performance with five preferred detection modes for a wide range of applications. Also for: Spectramax m4, Spectramax m5e, Spectramax m5. Standard features include a cuvette port, spectral scanning in 1 nm increments, and up to six wavelengths per read. Tissue accumulation of homocysteine occurs in classical homocystinuria, a metabolic disease characterized biochemically by cystathionine β-synthase deficiency. It can be used to assess biomolecular interactions, including protein-antibody binding and DNA hybridization, as well as enzyme activity, and it has been adapted to basic research as well as high-throughput screening. Learn how we performed a multiplexed, primary human cell-based assay to fluorometrically measure inflammation markers using our SpectraMax microplate readers in this poster. We use cookies to personalize content and improve your browsing experience. The trademarks mentioned herein are the property of Molecular Devices, Inc. or their respective owners. The results showed that baicalein suppressed rotenone-induced apoptosis, and inhibited the accumulation of reactive oxidant species, ATP deficiency, mitochondrial membrane potential dissipation, and caspase-3/7 activation in a concentration-dependent manner, indicating that baicalein likely improved mitochondrial function. The SpectraMax ABS and ABS Plus absorbance microplate readers provide the flexibility, sensitivity, and convenience for a wide range of assays such as ELISAs, microbial growth, and protein quantitation.Both readers feature an 8-channel read head for fast reads and a subset feature our patented PathCheck™ Sensor. No. View online or download Molecular devices SpectraMax M5 User Manual The Analyst®, FlexStation® and SpectraMax® M5/M5e from Molecular Devices have received the LanthaScreen® Certified designation from Invitrogen™ which ensures that these readers are validated to strict standards in instrument se Assays encompass the areas of G protein-coupled receptors (GPCR), kinases and cel…, Control Standard Endotoxin (CSE) was reconstituted with the volume of LAL reagent water (LRW) indicated on the Certificate of Analysis included with the kit to yield a solution of 100…, HTRF is a versatile technology developed by Cisbio for detecting molecular interactions between biomolecules.1 Combining the features of fluorescence resonance energy transfer (FRET)…. We use cookies to personalize content and improve your browsing experience. Firstly, we investigated the effects of baicalein on rotenone-induced toxicity in PC12 cells. These results suggest that baicalein may be a mitochondria-targeted antioxidant and exerts neuroprotective effects on rotenone-induced neurotoxicity. Discover More: The ImageXpress ® Confocal HT.ai High-Content Imaging System combines premium hardware technology with IN Carta Image Analysis Software, a self-learning software analysis workflow for increased signal and ultra-fast 3D organoid screening. Enzyme-linked immunosorbent assays (ELISAs) are used to measure the amount of a specific protein, using a microplate format, and results are most often detected via absorbance in the visible wavelength range. Normal HDL confers protection against atherosclerosis by inhibiting the…. CKD results in oxidative stress, inflammation, and high-density lipoprotein (HDL) deficiency, which work in concert to promote atherosclerosis. One of the…, Endpoint readers are prolific in the laboratory since absorbance has become the detection of choice for many applications. The Analyst®, FlexStation® and SpectraMax® M5/M5e from Molecular Devices have received the LanthaScreen® Certified designation from Invitrogen™ which ensures that these readers are validated to strict standards in instrument se NanoRacks reconfigured the SpectraMax M5e, one of Molecular Devices’ most reliable, durable, and feature-rich microplate readers, to operate comfortably in the zero-gravity environment of the space station. These trademarks may not be used in any type of promotion or advertising without the prior written permission of Molecular Devices, Inc. M3-M5e_manual.book Page 2 Wednesday, July 7, 2010 2:09 PM SpectraMax i3x Multi-Mode Microplate Reader (Molecular Devices Cat. Chemiluminescent and fluorescent ELISA formats offer enhanced sensitivity for accurate quantitation of less abundant analytes. Multi-Mode Microplate Readers. Learn all about time-resolved fluorescence – TRF and TR-FRET including HTRF assays. The Molecular Devices Spectramax M5e Multimode Microplate Reader offers you accuracy of a dedicated single mode reader across 5 modes of detection including being certified for Cisbio Bioassays HTRF technology. SoftMax Pro GxP Software extends data acquisition and analysis solution into regulated laboratories working under GMP, GLP, and 21 CFR Part 11 for secure electronic records. Our team-oriented corporate culture ensures diversity of thought, perspective, and a strong relationship of trust. In recent years they have emerged as one of the most important classes of drug targets for cancer and many…, Cell viability assays are often performed to assess the effects of a variety of treatments, including drug candidates, pathway activators and inhibitors, and reporter genes. This video will give you the basics on setting up your Molecular Devices SpectraMax® M5e Microplate Reader to run Cisbio HTRF Assays. SpectraMax M2, M2e* SpectraMax M3, M4, M5, M5e* FilterMax™ Multi-Mode Detection Platform. Learn all about absorbance detection – how it works, how it’s measured, and how it can be used to calculate concentration. On LabX buyers can find a variety of SpectraMAX models for sale: 190, 384, 340 and the SpectraMAX M series. Listing# 733155 Molecular Devices SpectraMax M5e Microplate Reader; Listing# 733155 Molecular Devices SpectraMax M5e Microplate Reader. Read independent reviews on SpectraMax® M5 Multi-Mode Microplate Reader from Molecular Devices® on SelectScience . In addition, SoftMax Pro Software Providing our customers with innovative bioanalytical solutions for protein and cell biology for over 30 years. The new Molecular Devices instrument comes with a standard 1-year depot warranty service. View the Molecular Devices website Create your account today to get full access to integrated content and world-class customer service. SpectraMax M3 laboratory equipment pdf manual download. Sunnyvale, CA - May 17, 2011 - Today, Molecular Devices, a leading provider of instruments, software, and consumables for drug discovery and life sciences research, announced that NanoRacks, LLC has chosen the SpectraMax® … Seller's Acceptable Currency: €15,000.00 EUR Make An Offer. Become 21 CFR Part 11 compliant with SoftMax Pro 7.1.1 GxP Software. Genotyping is a process for analyzing genetic differences among individuals by examining their DNA sequences. 25-051-CI) 3D-Culture, Organoids, & Organs-on-Chips 2021, Ananda Devices and Molecular Devices launch strategic collaboration to automate imaging and customize analysis of nervous system on-a-chip, Molecular Devices unveils next-generation imaging system with deep learning technology, Imaging system from Molecular Devices helps Recursion produce the largest publicly available set of human cellular morphological data for COVID-19 therapeutic research, Molecular Devices, LLC. SpectraMax M5e Multi-Mode Microplate Reader | Molecular Devices Extensive suite of validation tools reduces the cost and time of validation by 50% as compared to using multiple platforms to collect and analyze data. Measure sample depth with no temperature dependency using the patented PathCheck® Sensor technology. SpectraMax® M5 Microplate Reader from Molecular Devices LLC Description The upgradeable SpectraMax M5 Multi-Mode Microplate Reader comes with the standard five modes of detection with the upgrade option to add HTRF at a later time. For example, a red cell-impermeant, DNA-binding dye only stains dead or dying cells whose membranes are compromised, while a green live-cell dye only fluoresces when metabolic enzymes are active. Providing our customers with innovative bioanalytical solutions for protein and cell biology for over 30 years. Learn all about fluorescence detection – what it is, how it works, and the instruments used to measure the fluorescence of a sample. i3x) SpectraMax MiniMax 300 Imaging Cytometer (Molecular Devices Cat. These robust readers have been placed in labs from Antarctica to the International Space Station. They contain a wide range of high-performance capabilities ideal for life science research & drug discovery screening…, Molecular Devices is a leading provider of high-performance bioanalytical measurement solutions for life science research, pharmaceutical development, and biotherapeutic discovery. All rights reserved. Designed to help researchers advance phenotypic screening of: Learn how scientists are advancing discovery with our products and solutions. Life sciences technology predictions for 2021, Molecular devices unveils next-generation imaging system with deep learning technology, Spectramax Glo Steady-Luc Reporter Assay Kit, Neurotransmitter Transporters Uptake Assay Kit, SpectraMax Injection cartridge with SmartInject Technology, Adjustable Petri Dish and Microplate Holder, CloneSelect Single-Cell Printer Cartridges, The ImageXpress ® Confocal HT.ai High-Content Imaging System. In addition to green fluorescent protein (GFP) from the jellyfish Aequorea victoria, there are now numerous others available from other species of jellyfish and reef coral. Integrate easily with our StakMax® Microplate Stacker for walk-away automation. D … 50 μL of standard was pipetted into the wells of a white…. Create your account today to get full access to integrated content and world-class customer service. However, this method is only able to measure down to about…, ATP standards ranging from 1 μM to 1 pM were prepared as a 10-fold serial dilution series in phosphate-buffered saline (PBS). All rights reserved. Molecular Devices Corporation 1311 Orleans Drive Sunnyvale, California 94089 Part # 0112-0056 Rev. ©2021 Molecular Devices, LLC. 5024062) NIH3T3 cells (ATCC Cat. Examples include ELISAs for quantitation of cytokines and…, Quantitation of cell proliferation using fluorescence allows one to easily monitor the effects of drugs and other experimental treatments on cell growth. SpectraMax M5e Multi-Mode Microplate Reader. In May 2011, Molecular Devices’ SpectraMax M5e became the first microplate reader in space when NanoRacks added it to their line of commercial research hardware on the International Space Station, providing researchers the ability to conduct microplate reader experiments in … The SpectraMax M5e Multi-Mode Microplate Reader features a triple-mode cuvette port, temperature control, microplate shaking, and the industry leading SoftMax Pro. Normal HDL confers protection against atherosclerosis by inhibiting the oxidation of lipids and lipoproteins and by retrieving surplus cholesterol and phospholipids from lipid-laden cells in the artery wall for disposal in the liver (reverse cholesterol transport).

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